Dexamethasone is widely used in both veterinary and human medical practices.However, it seems to cause some deleterious effects\non pregnancy probably by causing changes in the reproductive hormone levels and their corresponding receptor concentrations.\nThis study investigated the effects of dexamethasone on these parameters. Twenty healthy adult Yankasa sheep comprising 18 ewes\nand 2 rams were used for this study. Pregnancies were achieved by natural mating after estrus synchronization. Dexamethasone\nwas administered at 0.25mg/kg body weight on days 1, 3, and 5 during first trimester; days 51, 53, and 55 during second trimester;\nand days 101, 103, and 105 during the third trimester. Blood samples were collected biweekly for hormonal assay. Uterine biopsies\nwere harvested through caesarean section for immunohistochemical analysis. Results showed that dexamethasone significantly\n(
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